ZFYVE27

Across TCGA cell cohorts, ZFYVE27 RNA expression is significantly associated with the go_rna of many other GO terms, with 3,667 significant associations in total. BLOOD_Lymphoma shows the largest number of these associations.

The most reproducible ZFYVE27-associated GO terms across cancer lineages are Viral translational termination-reinitiation, Phospholipid biosynthetic process, and Cilium-dependent cell motility. Each is linked with ZFYVE27 in more than 14 cancer types. Because this analysis shows association rather than direction, both ZFYVE27-to-partner and partner-to-ZFYVE27 results are reported.

Each partner links to its own Q-omics profile. The box plot shows the strongest example, Viral translational termination-reinitiation grouped by ZFYVE27-low versus ZFYVE27-high in LARGE_INTESTINE.

RNA expression associated GO terms by consensus

Ranked by combined sampling and lineage consensus. X-score (ZFYVE27→partner) and Y-score (partner→ZFYVE27) are standardized regression coefficients; both directions are reported because the association is undirected. p-values are from the association test.

Lineage	Partner GO term	X-score	Y-score	p(X)	p(Y)	Sampling consensus	Lineage consensus
LARGE_INTESTINE	Viral translational termination-reinitiation →	+0.103	+0.731	<.001	<.001	3	15
UPPER_AERODIGESTIVE_TRACT	Phospholipid biosynthetic process →	+0.050	+0.961	.001	.001	3	13
UPPER_AERODIGESTIVE_TRACT	Cilium-dependent cell motility →	-0.101	-0.886	<.001	<.001	3	13
UPPER_AERODIGESTIVE_TRACT	Cilium or flagellum-dependent cell motility →	-0.101	-0.886	<.001	<.001	3	13
BONE	Pre-mRNA catabolic process →	+0.252	+0.691	<.001	.003	3	13
UPPER_AERODIGESTIVE_TRACT	Cilium movement involved in cell motility →	-0.104	-0.886	<.001	<.001	3	13

Each partner links to its Q-omics profile. Showing the 6 strongest of 3,667 associations by consensus.

Viral translational termination-reinitiation by ZFYVE27 expression — LARGE_INTESTINE

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