ZFYVE1

Across TCGA patient cohorts, ZFYVE1 protein abundance is significantly associated with the RNA expression of many other genes, with 9,157 significant associations in total. CCRCC shows the largest number of these associations.

The most reproducible ZFYVE1-associated genes across cancer lineages are DCAF5, VTI1B, and VIPAS39. Each is linked with ZFYVE1 in more than 7 cancer types. Because this analysis shows association rather than direction, both ZFYVE1-to-partner and partner-to-ZFYVE1 results are reported.

Each partner links to its own Q-omics profile. The scatter plot shows the strongest example, ZFYVE1 versus DCAF5 in OV, with a Pearson correlation of 0.44.

protein abundance associated genes by consensus

Ranked by combined sampling and lineage consensus. X-score (ZFYVE1→partner) and Y-score (partner→ZFYVE1) are standardized regression coefficients; both directions are reported because the association is undirected. p-values are from the association test.

Lineage	Partner gene	X-score	Y-score	p(X)	p(Y)	Sampling consensus	Lineage consensus
OV	DCAF5 →	+0.528	+0.268	.001	.002	3	8
HNSC	VTI1B →	+0.517	+0.271	.009	<.001	2	8
LUAD	VIPAS39 →	+0.455	+0.248	<.001	<.001	3	7
CCRCC	ABCD4 →	+0.374	+0.152	<.001	<.001	3	7
OV	PTPN21 →	+0.827	+0.337	<.001	.001	3	7
BRCA	CGRRF1 →	+0.463	+0.197	<.001	<.001	3	6

Each partner links to its Q-omics profile. Showing the 6 strongest of 9,157 associations by consensus.

ZFYVE1 vs DCAF5 — OV

Explore this scatter interactively →