ZFPM2

RNA expression — cross-omics
Cross-omicsRNA → FUNCTION-RNACell-linePairwise association · TCGA cohorts

Across TCGA cell cohorts, ZFPM2 RNA expression is significantly associated with the go_rna of many other GO terms, with 3,044 significant associations in total. SKIN shows the largest number of these associations.

The most reproducible ZFPM2-associated GO terms across cancer lineages are Positive regulation of cell-substrate junction organization, Regulation of telomere maintenance, and Positive regulation of chromosome organization. Each is linked with ZFPM2 in more than 8 cancer types. Because this analysis shows association rather than direction, both ZFPM2-to-partner and partner-to-ZFPM2 results are reported.

Each partner links to its own Q-omics profile. The box plot shows the strongest example, Positive regulation of cell-substrate junction organization grouped by ZFPM2-low versus ZFPM2-high in SKIN.

RNA expression associated GO terms by consensus

Ranked by combined sampling and lineage consensus. X-score (ZFPM2→partner) and Y-score (partner→ZFPM2) are standardized regression coefficients; both directions are reported because the association is undirected. p-values are from the association test.
LineagePartner GO termX-scoreY-scorep(X)p(Y)Sampling consensusLineage consensus
SKINPositive regulation of cell-substrate junction organization →+0.072+0.417<.001<.00139
LARGE_INTESTINERegulation of telomere maintenance →+0.052+0.365<.001<.00138
LARGE_INTESTINEPositive regulation of chromosome organization →+0.067+0.720<.001.00138
SKINProtein localization to nucleus →+0.040+0.481.001.00137
UPPER_AERODIGESTIVE_TRACTRegulation of postsynaptic membrane potential →-0.125-0.540.004.00637
SKINRescue of stalled cytosolic ribosome →+0.075+0.559<.001.00137
Each partner links to its Q-omics profile. Showing the 6 strongest of 3,044 associations by consensus.

Positive regulation of cell-substrate junction organization by ZFPM2 expression — SKIN

Box plot of Positive regulation of cell-substrate junction organization in ZFPM2-low vs ZFPM2-high samples in SKIN.

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