ZFPM2

Across TCGA cell cohorts, ZFPM2 mutation is significantly associated with the RNA expression of many other genes, with 1,455 significant associations in total. LARGE_INTESTINE shows the largest number of these associations.

The most reproducible ZFPM2-associated genes across cancer lineages are OR51J1, IRGC, and OR51B4. Each is linked with ZFPM2 in more than 2 cancer types. Because this analysis shows association rather than direction, both ZFPM2-to-partner and partner-to-ZFPM2 results are reported.

Each partner links to its own Q-omics profile. The box plot shows the strongest example, OR51J1 grouped by ZFPM2-low versus ZFPM2-high in LUNG_NSCLC_LUAD.

mutation associated genes by consensus

Ranked by combined sampling and lineage consensus. X-score (ZFPM2→partner) and Y-score (partner→ZFPM2) are standardized regression coefficients; both directions are reported because the association is undirected. p-values are from the association test.

Lineage	Partner gene	X-score	Y-score	p(X)	p(Y)	Sampling consensus	Lineage consensus
LUNG_NSCLC_LUAD	OR51J1 →	+0.154	+2.285	<.001	<.001	3	3
LUNG_SCLC	IRGC →	+0.027	+2.898	.002	.001	3	2
LUNG_SCLC	OR51B4 →	+1.003	+3.667	<.001	<.001	3	2
SKIN	BLID →	+0.193	+2.521	.001	.002	3	2
CNS	AGXT2 →	+0.014	+3.643	<.001	.007	3	2
CNS	CCR5 →	+0.117	+4.087	<.001	.004	3	2

Each partner links to its Q-omics profile. Showing the 6 strongest of 1,455 associations by consensus.

OR51J1 by ZFPM2 expression — LUNG_NSCLC_LUAD

Explore this box plot interactively →