ZFPM1

Across TCGA pan-cancer cohorts, ZFPM1 mass-spec protein is linked to patient survival in 4 of 34 cancer types, making it a survival-associated ZFPM1 data layer compared with 27 for mass-spec protein and 4 for mutation status.

The strongest signal is observed in pancreatic ductal adenocarcinoma (PDAC), where higher ZFPM1 mass-spec protein is associated with better overall survival. In most high-consensus cancer types, elevated ZFPM1 expression acts as an unfavorable survival marker, although some lineages such as PDAC show a favorable association.

PDAC, LUAD, and LSCC are the cancer types where ZFPM1 mass-spec protein most reproducibly stratifies survival.

mass-spec protein survival associations by lineage

Ranked by sampling consensus. AUC1 and AUC2 indicate survival in the high- and low-expression groups, respectively; the lower AUC marks the poorer-surviving group. p-values are from the log-rank test.

Lineage	Measure	Split	Stage	AUC1 high	AUC2 low	p	Sampling consensus
PDAC	OS	Tertile	II,III,IV	1.000	0.749	.011	6	view →
LUAD	OS	Median	II,III,IV	0.418	1.000	.017	4	view →
LSCC	DFS	Median	All	0.764	0.949	.037	2	view →
GBM	DFS	Median	All	0.156	0.623	.024	2	view →

Pink = unfavorable, green = favorable. Showing the 4 strongest of 4 lineages.

ZFPM1–PDAC (OS)

Open the PDAC breakdown →