ZFPM1

Across TCGA cell cohorts, ZFPM1 RNA expression is significantly associated with the go_rna of many other GO terms, with 4,174 significant associations in total. BLOOD_Leukemia shows the largest number of these associations.

The most reproducible ZFPM1-associated GO terms across cancer lineages are Negative regulation of calcium ion export across plasma membrane, Negative regulation of syncytium formation by plasma membrane fusion, and Negative regulation of interleukin-4 production. Each is linked with ZFPM1 in more than 12 cancer types. Because this analysis shows association rather than direction, both ZFPM1-to-partner and partner-to-ZFPM1 results are reported.

Each partner links to its own Q-omics profile. The box plot shows the strongest example, Negative regulation of calcium ion export across plasma membrane grouped by ZFPM1-low versus ZFPM1-high in BONE.

RNA expression associated GO terms by consensus

Ranked by combined sampling and lineage consensus. X-score (ZFPM1→partner) and Y-score (partner→ZFPM1) are standardized regression coefficients; both directions are reported because the association is undirected. p-values are from the association test.

Lineage	Partner GO term	X-score	Y-score	p(X)	p(Y)	Sampling consensus	Lineage consensus
BONE	Negative regulation of calcium ion export across plasma membrane →	+0.075	+0.909	<.001	.001	3	13
BREAST	Negative regulation of syncytium formation by plasma membrane fusion →	+0.093	+0.624	.001	.004	3	11
PANCREAS	Negative regulation of interleukin-4 production →	-0.405	-0.696	<.001	<.001	3	11
UPPER_AERODIGESTIVE_TRACT	Viral translational termination-reinitiation →	+0.114	+0.679	<.001	<.001	3	11
UPPER_AERODIGESTIVE_TRACT	Endosomal vesicle fusion →	+0.066	+0.505	.001	<.001	3	11
STOMACH	Mitral valve formation →	+0.892	+1.308	<.001	<.001	3	11

Each partner links to its Q-omics profile. Showing the 6 strongest of 4,174 associations by consensus.

Negative regulation of calcium ion export across plasma membrane by ZFPM1 expression — BONE

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