ZFPM1

Across TCGA cell cohorts, ZFPM1 mutation is significantly associated with the RNA expression of many other genes, with 523 significant associations in total. LARGE_INTESTINE shows the largest number of these associations.

The most reproducible ZFPM1-associated genes across cancer lineages are FAM187B, GRM6, and G6PC3. Each is linked with ZFPM1 in more than 1 cancer types. Because this analysis shows association rather than direction, both ZFPM1-to-partner and partner-to-ZFPM1 results are reported.

Each partner links to its own Q-omics profile. The box plot shows the strongest example, FAM187B grouped by ZFPM1-low versus ZFPM1-high in SOFT_TISSUE.

mutation associated genes by consensus

Ranked by combined sampling and lineage consensus. X-score (ZFPM1→partner) and Y-score (partner→ZFPM1) are standardized regression coefficients; both directions are reported because the association is undirected. p-values are from the association test.

Lineage	Partner gene	X-score	Y-score	p(X)	p(Y)	Sampling consensus	Lineage consensus
SOFT_TISSUE	FAM187B →	+0.019	+4.369	<.001	.008	3	2
LARGE_INTESTINE	GRM6 →	+0.041	+2.208	.007	.001	3	2
LARGE_INTESTINE	G6PC3 →	-0.543	-2.541	<.001	.005	3	2
LARGE_INTESTINE	PNLDC1 →	+0.057	+3.321	.003	.003	3	2
LARGE_INTESTINE	SERF1B →	+0.606	+3.389	.001	.001	3	2
LARGE_INTESTINE	ALG3 →	-0.448	-2.541	.002	.005	3	2

Each partner links to its Q-omics profile. Showing the 6 strongest of 523 associations by consensus.

FAM187B by ZFPM1 expression — SOFT_TISSUE

Explore this box plot interactively →