ZFP91-CNTF

Across TCGA pan-cancer cohorts, ZFP91-CNTF RNA differs between tumor and matched normal tissue in 7 of 18 cancer types tested, making tumor–normal expression one of ZFP91-CNTF’s most consistent transcriptional readouts.

The strongest signal is observed in head and neck squamous cell carcinoma (HNSC), where ZFP91-CNTF RNA is more highly expressed in tumor relative to normal tissue. In most cancer types ZFP91-CNTF is over-expressed in tumor, although a few such as THCA and COAD show the opposite, repressed pattern.

HNSC, LIHC, and STAD are the cancer types where ZFP91-CNTF tumor–normal differential expression is most reproducible.

RNA tumor vs normal associations by lineage

Ranked by sampling consensus. Fold-change is the tumor-versus-normal difference in ZFP91-CNTF RNA (log₂); positive values indicate higher expression in tumor. p-values are from the differential-expression test.

Lineage	Gender	Stage	Fold-change	p	Sampling consensus
HNSC	Male	All	+0.072	<.001	10	view →
LIHC	All	All	+0.021	.003	5	view →
STAD	Male	All	+0.040	.024	3	view →
THCA	Male	II,III,IV	−0.036	.020	2	view →
COAD	Female	All	−0.028	.012	2	view →
BRCA	All	II,III,IV	+0.020	.031	2	view →
LUSC	All	II,III,IV	+0.047	.031	1	view →

Pink = over-expressed in tumor, green = repressed in tumor. Showing the 7 strongest of 7 lineages.

ZFP91-CNTF–HNSC

Open the HNSC breakdown →