Across TCGA pan-cancer cohorts, ZFP69B RNA is linked to patient survival in 27 of 34 cancer types, making it the most broadly survival-associated ZFP69B data layer compared with 3 for mutation status.

The strongest signal is observed in liver hepatocellular carcinoma (LIHC), where higher ZFP69B RNA is associated with worse overall survival. In most high-consensus cancer types, elevated ZFP69B expression acts as an unfavorable survival marker, although some lineages such as OV and UCS show a favorable association.

LIHC, MESO, and OV are the cancer types where ZFP69B RNA most reproducibly stratifies survival.

RNA survival associations by lineage

Ranked by sampling consensus. AUC1 and AUC2 indicate survival in the high- and low-expression groups, respectively; the lower AUC marks the poorer-surviving group. p-values are from the log-rank test.

Lineage	Measure	Split	Stage	AUC1 high	AUC2 low	p	Sampling consensus
LIHC	OS	Median	All	0.713	0.835	<.001	99	view →
MESO	DFS	Quartile	All	0.236	0.502	.002	40	view →
OV	DFS	Median	II,III,IV	0.415	0.345	.018	30	view →
LUSC	DFS	Tertile	III,IV	0.087	0.870	<.001	26	view →
SARC	OS	Tertile	All	0.396	0.688	<.001	26	view →
UCS	OS	Quartile	II,III,IV	0.735	0.229	.003	24	view →
GBM	DFS	Median	All	0.397	0.173	<.001	24	view →
READ	OS	Quartile	All	0.800	0.413	.016	22	view →
ACC	DFS	Quartile	All	0.508	0.851	.003	17	view →
HNSC	OS	Tertile	All	0.809	0.697	.018	14	view →
TGCT	DFS	Median	All	0.932	0.731	.004	12	view →
BLCA	DFS	Tertile	All	0.245	0.503	.015	12	view →

Pink = unfavorable, green = favorable. Showing the 12 strongest of 27 lineages.

Exploration

Same gene, other analysis: ZFP69B tumor-vs-normal RNA expression · all ZFP69B data types