Across TCGA patient cohorts, ZFP69 mutation is significantly associated with the total protein of many other genes, with 23 significant associations in total. UCEC shows the largest number of these associations.

The most reproducible ZFP69-associated genes across cancer lineages are Beclin, Dvl3, and Gab2. Each is linked with ZFP69 in more than 1 cancer types. Because this analysis shows association rather than direction, both ZFP69-to-partner and partner-to-ZFP69 results are reported.

Each partner links to its own Q-omics profile.

mutation associated genes by consensus

Ranked by combined sampling and lineage consensus. X-score (ZFP69→partner) and Y-score (partner→ZFP69) are standardized regression coefficients; both directions are reported because the association is undirected. p-values are from the association test.

Lineage	Partner gene	X-score	Y-score	p(X)	p(Y)	Sampling consensus	Lineage consensus
UCEC	Beclin →	+0.146	+2.807	<.001	.003	3	2
UCEC	Dvl3 →	+0.164	+2.321	.041	.034	3	2
UCEC	Gab2 →	+0.502	+2.321	.001	.034	3	1
UCEC	Acetyl-a-Tubulin-Lys40 →	+0.613	+2.331	.005	.019	3	1
UCEC	JNK_pT183_Y185 →	-0.191	-2.584	.009	.010	3	1
UCEC	MEK1 →	+0.394	+3.169	.013	.018	3	1

Each partner links to its Q-omics profile. Showing the 6 strongest of 23 associations by consensus.

Exploration

ZFP69 survival (RNA) · tumor vs normal (RNA) · all ZFP69 data types