Across TCGA pan-cancer cohorts, ZFP69 RNA is linked to patient survival in 23 of 34 cancer types, making it the most broadly survival-associated ZFP69 data layer compared with 7 for mutation status.
The strongest signal is observed in head and neck squamous cell carcinoma (HNSC), where higher ZFP69 RNA is associated with better disease-free survival. In most high-consensus cancer types, elevated ZFP69 expression acts as an unfavorable survival marker, although some lineages such as HNSC and BRCA show a favorable association.
HNSC, BRCA, and READ are the cancer types where ZFP69 RNA most reproducibly stratifies survival.
RNA survival associations by lineage
Ranked by sampling consensus. AUC1 and AUC2 indicate survival in the high- and low-expression groups, respectively; the lower AUC marks the poorer-surviving group. p-values are from the log-rank test.