ZFP42

Across TCGA patient cohorts, ZFP42 RNA expression is significantly associated with the go_rna of many other GO terms, with 6,396 significant associations in total. STAD shows the largest number of these associations.

The most reproducible ZFP42-associated GO terms across cancer lineages are AMP biosynthetic process, Maturation of 5.8S rRNA, and Endonucleolytic cleavage of tricistronic rRNA transcript (SSU-rRNA, 5.8S rRNA, LSU-rRNA). Each is linked with ZFP42 in more than 11 cancer types. Because this analysis shows association rather than direction, both ZFP42-to-partner and partner-to-ZFP42 results are reported.

Each partner links to its own Q-omics profile. The box plot shows the strongest example, AMP biosynthetic process grouped by ZFP42-low versus ZFP42-high in ESCA.

RNA expression associated GO terms by consensus

Ranked by combined sampling and lineage consensus. X-score (ZFP42→partner) and Y-score (partner→ZFP42) are standardized regression coefficients; both directions are reported because the association is undirected. p-values are from the association test.

Lineage	Partner GO term	X-score	Y-score	p(X)	p(Y)	Sampling consensus	Lineage consensus
ESCA	AMP biosynthetic process →	+0.061	+0.806	.001	.002	3	12
STAD	Maturation of 5.8S rRNA →	+0.111	+0.540	<.001	<.001	3	12
STAD	Endonucleolytic cleavage of tricistronic rRNA transcript (SSU-rRNA, 5.8S rRNA, LSU-rRNA) →	+0.063	+0.341	<.001	<.001	3	11
STAD	Protein localization to nuclear envelope →	+0.120	+0.589	<.001	<.001	3	11
ESCA	GMP biosynthetic process →	+0.069	+0.738	<.001	.002	3	11
STAD	Nucleoside monophosphate biosynthetic process →	+0.093	+0.382	<.001	.001	3	11

Each partner links to its Q-omics profile. Showing the 6 strongest of 6,396 associations by consensus.

AMP biosynthetic process by ZFP42 expression — ESCA

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