ZFP42

Across TCGA patient cohorts, ZFP42 mutation is significantly associated with the total protein of many other genes, with 38 significant associations in total. UCEC shows the largest number of these associations.

The most reproducible ZFP42-associated genes across cancer lineages are FoxM1, PCNA, and Di-Ras3. Each is linked with ZFP42 in more than 3 cancer types. Because this analysis shows association rather than direction, both ZFP42-to-partner and partner-to-ZFP42 results are reported.

Each partner links to its own Q-omics profile. The box plot shows the strongest example, FoxM1 grouped by ZFP42-low versus ZFP42-high in UCEC.

mutation associated genes by consensus

Ranked by combined sampling and lineage consensus. X-score (ZFP42→partner) and Y-score (partner→ZFP42) are standardized regression coefficients; both directions are reported because the association is undirected. p-values are from the association test.

Lineage	Partner gene	X-score	Y-score	p(X)	p(Y)	Sampling consensus	Lineage consensus
UCEC	FoxM1 →	+0.185	+1.459	.027	.012	3	4
COAD	PCNA →	+0.284	+3.178	.020	.010	3	3
COAD	Di-Ras3 →	-0.246	-3.161	.010	.019	3	3
UCEC	eIF4E →	+0.189	+3.820	.005	<.001	3	3
UCEC	MEK1 →	+0.341	+2.169	.004	.003	3	2
COAD	Shc_pY317 →	-0.175	-2.987	.034	.035	3	2

Each partner links to its Q-omics profile. Showing the 6 strongest of 38 associations by consensus.

FoxM1 by ZFP42 expression — UCEC

Explore this box plot interactively →