ZFP36L1

mutation — cross-omics
Cross-omicsMUTATION → RNAPatientPairwise association · TCGA cohorts

Across TCGA patient cohorts, ZFP36L1 mutation is significantly associated with the RNA expression of many other genes, with 2,366 significant associations in total. UCEC shows the largest number of these associations.

The most reproducible ZFP36L1-associated genes across cancer lineages are RBM11P1, MIR302A, and RN7SL488P. Each is linked with ZFP36L1 in more than 2 cancer types. Because this analysis shows association rather than direction, both ZFP36L1-to-partner and partner-to-ZFP36L1 results are reported.

Each partner links to its own Q-omics profile.

mutation associated genes by consensus

Ranked by combined sampling and lineage consensus. X-score (ZFP36L1→partner) and Y-score (partner→ZFP36L1) are standardized regression coefficients; both directions are reported because the association is undirected. p-values are from the association test.
LineagePartner geneX-scoreY-scorep(X)p(Y)Sampling consensusLineage consensus
CESCRBM11P1 →+0.051+2.969<.001.00733
HNSCMIR302A →+0.432+3.780<.001.00733
HNSCRN7SL488P →+0.102+3.813.008.00733
UCECMIR615 →+0.177+1.910.003.00833
LUSCRNVU1-33 →+0.218+3.679<.001.00133
BRCABCAR1P2 →+0.064+4.994<.001<.00132
Each partner links to its Q-omics profile. Showing the 6 strongest of 2,366 associations by consensus.

Exploration