ZFP36

Across TCGA patient cohorts, ZFP36 protein abundance is significantly associated with the RNA expression of many other genes, with 5,773 significant associations in total. HNSC shows the largest number of these associations.

The most reproducible ZFP36-associated genes across cancer lineages are NAMPT, HBEGF, and EGR1. Each is linked with ZFP36 in more than 3 cancer types. Because this analysis shows association rather than direction, both ZFP36-to-partner and partner-to-ZFP36 results are reported.

Each partner links to its own Q-omics profile. The scatter plot shows the strongest example, ZFP36 versus NAMPT in HNSC, with a Pearson correlation of 0.25.

protein abundance associated genes by consensus

Ranked by combined sampling and lineage consensus. X-score (ZFP36→partner) and Y-score (partner→ZFP36) are standardized regression coefficients; both directions are reported because the association is undirected. p-values are from the association test.

Lineage	Partner gene	X-score	Y-score	p(X)	p(Y)	Sampling consensus	Lineage consensus
HNSC	NAMPT →	+0.835	+0.461	.003	.002	3	4
LUAD	HBEGF →	+1.172	+0.428	<.001	<.001	3	3
BRCA	EGR1 →	+1.490	+0.550	.001	.001	3	3
HNSC	CDKN1A →	+1.011	+0.798	<.001	<.001	3	3
BRCA	FOSB →	+2.151	+0.570	.001	.009	3	3
LUAD	KLF4 →	+1.046	+0.449	<.001	<.001	3	3

Each partner links to its Q-omics profile. Showing the 6 strongest of 5,773 associations by consensus.

ZFP36 vs NAMPT — HNSC

Explore this scatter interactively →