ZFP30

Across TCGA cell cohorts, ZFP30 mutation is significantly associated with the RNA expression of many other genes, with 12 significant associations in total. BLOOD_Leukemia shows the largest number of these associations.

The most reproducible ZFP30-associated genes across cancer lineages are LGI1, ACTRT1, and AMELX. Each is linked with ZFP30 in more than 1 cancer types. Because this analysis shows association rather than direction, both ZFP30-to-partner and partner-to-ZFP30 results are reported.

Each partner links to its own Q-omics profile. The box plot shows the strongest example, LGI1 grouped by ZFP30-low versus ZFP30-high in BLOOD_Leukemia.

mutation associated genes by consensus

Ranked by combined sampling and lineage consensus. X-score (ZFP30→partner) and Y-score (partner→ZFP30) are standardized regression coefficients; both directions are reported because the association is undirected. p-values are from the association test.

Lineage	Partner gene	X-score	Y-score	p(X)	p(Y)	Sampling consensus	Lineage consensus
BLOOD_Leukemia	LGI1 →	+0.129	+5.539	<.001	.003	3	1
BLOOD_Leukemia	ACTRT1 →	+0.028	+5.201	<.001	.006	3	1
BLOOD_Leukemia	AMELX →	+0.038	+5.539	<.001	.003	3	1
BLOOD_Leukemia	C1QL2 →	+0.019	+4.922	<.001	.009	3	1
BLOOD_Leukemia	SPHKAP →	+0.012	+4.922	<.001	.009	3	1
BLOOD_Leukemia	ACTRT2 →	+0.064	+4.922	.001	.009	3	1

Each partner links to its Q-omics profile. Showing the 6 strongest of 12 associations by consensus.

LGI1 by ZFP30 expression — BLOOD_Leukemia

Explore this box plot interactively →