ZFHX2

Across TCGA patient cohorts, ZFHX2 protein abundance is significantly associated with the RNA expression of many other genes, with 30 significant associations in total. CCRCC shows the largest number of these associations.

The most reproducible ZFHX2-associated genes across cancer lineages are ADAMTS1, KCMF1, and PDE4B. Each is linked with ZFHX2 in more than 1 cancer types. Because this analysis shows association rather than direction, both ZFHX2-to-partner and partner-to-ZFHX2 results are reported.

Each partner links to its own Q-omics profile. The scatter plot shows the strongest example, ZFHX2 versus ADAMTS1 in CCRCC, with a Pearson correlation of -0.90.

protein abundance associated genes by consensus

Ranked by combined sampling and lineage consensus. X-score (ZFHX2→partner) and Y-score (partner→ZFHX2) are standardized regression coefficients; both directions are reported because the association is undirected. p-values are from the association test.

Lineage	Partner gene	X-score	Y-score	p(X)	p(Y)	Sampling consensus	Lineage consensus
CCRCC	ADAMTS1 →	-2.043	-1.290	.003	.006	3	1
CCRCC	KCMF1 →	-0.388	-2.008	.009	.007	3	1
CCRCC	PDE4B →	-1.459	-1.290	.001	.006	3	1
CCRCC	BAZ1A →	-0.541	-1.290	<.001	.006	3	1
CCRCC	RNU6-301P →	-2.374	-1.290	<.001	.006	3	1
CCRCC	CCNYL4 →	-0.346	-1.290	.002	.006	3	1

Each partner links to its Q-omics profile. Showing the 6 strongest of 30 associations by consensus.

ZFHX2 vs ADAMTS1 — CCRCC

Explore this scatter interactively →