ZFAT-AS1

Across TCGA patient cohorts, ZFAT-AS1 RNA expression is significantly associated with the go_rna of many other GO terms, with 3,931 significant associations in total. STAD shows the largest number of these associations.

The most reproducible ZFAT-AS1-associated GO terms across cancer lineages are Regulation of receptor-mediated endocytosis, Intracellular glucose homeostasis, and Positive regulation of protein ubiquitination. Each is linked with ZFAT-AS1 in more than 6 cancer types. Because this analysis shows association rather than direction, both ZFAT-AS1-to-partner and partner-to-ZFAT-AS1 results are reported.

Each partner links to its own Q-omics profile. The box plot shows the strongest example, Regulation of receptor-mediated endocytosis grouped by ZFAT-AS1-low versus ZFAT-AS1-high in UVM.

RNA expression associated GO terms by consensus

Ranked by combined sampling and lineage consensus. X-score (ZFAT-AS1→partner) and Y-score (partner→ZFAT-AS1) are standardized regression coefficients; both directions are reported because the association is undirected. p-values are from the association test.

Lineage	Partner GO term	X-score	Y-score	p(X)	p(Y)	Sampling consensus	Lineage consensus
UVM	Regulation of receptor-mediated endocytosis →	+0.033	+0.015	<.001	.006	2	7
STAD	Intracellular glucose homeostasis →	+0.030	+0.025	<.001	.003	3	6
COAD	Positive regulation of protein ubiquitination →	+0.055	+0.027	<.001	.002	3	6
COAD	Regulation of microtubule-based process →	+0.041	+0.030	<.001	.006	3	6
COAD	Signal transduction in response to DNA damage →	+0.053	+0.015	<.001	.002	3	6
STAD	Cell cycle G1/S phase transition →	+0.034	+0.018	<.001	<.001	3	6

Each partner links to its Q-omics profile. Showing the 6 strongest of 3,931 associations by consensus.

Regulation of receptor-mediated endocytosis by ZFAT-AS1 expression — UVM

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