ZFAND3

Across TCGA patient cohorts, ZFAND3 mutation is significantly associated with the RNA expression of many other genes, with 2,328 significant associations in total. UCEC shows the largest number of these associations.

The most reproducible ZFAND3-associated genes across cancer lineages are BTBD10, LIN7C, and IMMP1L. Each is linked with ZFAND3 in more than 1 cancer types. Because this analysis shows association rather than direction, both ZFAND3-to-partner and partner-to-ZFAND3 results are reported.

Each partner links to its own Q-omics profile. The box plot shows the strongest example, BTBD10 grouped by ZFAND3-low versus ZFAND3-high in UCEC.

mutation associated genes by consensus

Ranked by combined sampling and lineage consensus. X-score (ZFAND3→partner) and Y-score (partner→ZFAND3) are standardized regression coefficients; both directions are reported because the association is undirected. p-values are from the association test.

Lineage	Partner gene	X-score	Y-score	p(X)	p(Y)	Sampling consensus	Lineage consensus
UCEC	BTBD10 →	+0.447	+3.617	.001	.001	3	1
UCEC	LIN7C →	+0.565	+2.743	<.001	.002	3	1
UCEC	IMMP1L →	+0.368	+2.354	.003	.003	3	1
UCEC	APIP →	+0.421	+3.593	.005	.001	3	1
UCEC	EIF3M →	+0.423	+3.743	.003	<.001	3	1
UCEC	SSRP1 →	+0.429	+2.254	.008	.005	3	1

Each partner links to its Q-omics profile. Showing the 6 strongest of 2,328 associations by consensus.

BTBD10 by ZFAND3 expression — UCEC

Explore this box plot interactively →