ZEB2

Across TCGA cell cohorts, ZEB2 RNA expression is significantly associated with the go_rna of many other GO terms, with 5,405 significant associations in total. BLOOD_Leukemia shows the largest number of these associations.

The most reproducible ZEB2-associated GO terms across cancer lineages are Positive regulation of actin filament-based movement, Response to oscillatory fluid shear stress, and Cellular response to oscillatory fluid shear stress. Each is linked with ZEB2 in more than 11 cancer types. Because this analysis shows association rather than direction, both ZEB2-to-partner and partner-to-ZEB2 results are reported.

Each partner links to its own Q-omics profile. The box plot shows the strongest example, Positive regulation of actin filament-based movement grouped by ZEB2-low versus ZEB2-high in URINARY_TRACT.

RNA expression associated GO terms by consensus

Ranked by combined sampling and lineage consensus. X-score (ZEB2→partner) and Y-score (partner→ZEB2) are standardized regression coefficients; both directions are reported because the association is undirected. p-values are from the association test.

Lineage	Partner GO term	X-score	Y-score	p(X)	p(Y)	Sampling consensus	Lineage consensus
URINARY_TRACT	Positive regulation of actin filament-based movement →	+1.344	+2.506	<.001	<.001	3	12
STOMACH	Response to oscillatory fluid shear stress →	+0.209	+1.535	<.001	.001	3	12
STOMACH	Cellular response to oscillatory fluid shear stress →	+0.209	+1.535	<.001	.001	3	12
STOMACH	Vascular endothelial cell response to oscillatory fluid shear stress →	+0.209	+1.535	<.001	.001	3	12
LUNG_NSCLC_LUSC	Establishment or maintenance of microtubule cytoskeleton polarity →	+0.224	+2.627	<.001	<.001	3	12
BREAST	Biological process involved in interaction with symbiont →	+0.263	+2.175	<.001	<.001	3	12

Each partner links to its Q-omics profile. Showing the 6 strongest of 5,405 associations by consensus.

Positive regulation of actin filament-based movement by ZEB2 expression — URINARY_TRACT

Explore this box plot interactively →