Across TCGA patient cohorts, ZDHHC9 mutation is significantly associated with the total protein of many other genes, with 24 significant associations in total. UCEC shows the largest number of these associations.

The most reproducible ZDHHC9-associated genes across cancer lineages are PDCD4, STAT3_pY705, and ATM. Each is linked with ZDHHC9 in more than 1 cancer types. Because this analysis shows association rather than direction, both ZDHHC9-to-partner and partner-to-ZDHHC9 results are reported.

Each partner links to its own Q-omics profile.

mutation associated genes by consensus

Ranked by combined sampling and lineage consensus. X-score (ZDHHC9→partner) and Y-score (partner→ZDHHC9) are standardized regression coefficients; both directions are reported because the association is undirected. p-values are from the association test.

Lineage	Partner gene	X-score	Y-score	p(X)	p(Y)	Sampling consensus	Lineage consensus
UCEC	PDCD4 →	-0.425	-1.392	.006	.019	3	2
UCEC	STAT3_pY705 →	-0.330	-2.087	<.001	.004	3	2
UCEC	ATM →	-0.565	-2.308	<.001	.005	3	2
UCEC	4E-BP1_pT37_T46 →	-0.289	-2.571	.019	.010	3	2
UCEC	Chk2_pT68 →	-0.152	-2.990	.013	<.001	3	2
UCEC	4E-BP1 →	+0.195	+3.459	.029	.005	3	2

Each partner links to its Q-omics profile. Showing the 6 strongest of 24 associations by consensus.

Exploration

ZDHHC9 survival (RNA) · tumor vs normal (RNA) · all ZDHHC9 data types