ZDHHC7

Across TCGA patient cohorts, ZDHHC7 mutation is significantly associated with the RNA expression of many other genes, with 2,541 significant associations in total. UCEC shows the largest number of these associations.

The most reproducible ZDHHC7-associated genes across cancer lineages are LINC02210-CRHR1, SNX3P1X, and RNY1P1. Each is linked with ZDHHC7 in more than 1 cancer types. Because this analysis shows association rather than direction, both ZDHHC7-to-partner and partner-to-ZDHHC7 results are reported.

Each partner links to its own Q-omics profile. The box plot shows the strongest example, LINC02210-CRHR1 grouped by ZDHHC7-low versus ZDHHC7-high in UCEC.

mutation associated genes by consensus

Ranked by combined sampling and lineage consensus. X-score (ZDHHC7→partner) and Y-score (partner→ZDHHC7) are standardized regression coefficients; both directions are reported because the association is undirected. p-values are from the association test.

Lineage	Partner gene	X-score	Y-score	p(X)	p(Y)	Sampling consensus	Lineage consensus
UCEC	LINC02210-CRHR1 →	+0.064	+2.043	<.001	.002	3	2
SKCM	SNX3P1X →	+0.200	+4.884	<.001	.004	3	2
UCEC	RNY1P1 →	+0.124	+2.635	.002	.003	3	2
UCEC	SNORD116-23 →	+0.385	+1.460	.002	.005	3	2
UCEC	RNU6-440P →	+0.081	+2.879	.003	.007	3	2
UCEC	LYPLA1P1 →	+0.032	+2.879	<.001	.007	3	2

Each partner links to its Q-omics profile. Showing the 6 strongest of 2,541 associations by consensus.

LINC02210-CRHR1 by ZDHHC7 expression — UCEC

Explore this box plot interactively →