ZDHHC6

Across TCGA patient cohorts, ZDHHC6 protein abundance is significantly associated with the RNA expression of many other genes, with 2,538 significant associations in total. UCEC shows the largest number of these associations.

The most reproducible ZDHHC6-associated genes across cancer lineages are CYP4F29P, ENPP7P9, and MIR3153. Each is linked with ZDHHC6 in more than 1 cancer types. Because this analysis shows association rather than direction, both ZDHHC6-to-partner and partner-to-ZDHHC6 results are reported.

Each partner links to its own Q-omics profile. The scatter plot shows the strongest example, ZDHHC6 versus CYP4F29P in PDAC, with a Pearson correlation of -0.47.

protein abundance associated genes by consensus

Ranked by combined sampling and lineage consensus. X-score (ZDHHC6→partner) and Y-score (partner→ZDHHC6) are standardized regression coefficients; both directions are reported because the association is undirected. p-values are from the association test.

Lineage	Partner gene	X-score	Y-score	p(X)	p(Y)	Sampling consensus	Lineage consensus
PDAC	CYP4F29P →	-0.873	-0.570	<.001	.001	3	2
COAD	ENPP7P9 →	+0.536	+0.446	.005	.003	3	2
COAD	MIR3153 →	+1.382	+0.389	.001	<.001	3	2
LSCC	PF4V1 →	+0.769	+0.193	.003	<.001	3	2
OV	RGN →	-1.242	-0.577	.007	<.001	3	2
LUAD	EIF5A →	+0.355	+0.240	.008	.007	3	2

Each partner links to its Q-omics profile. Showing the 6 strongest of 2,538 associations by consensus.

ZDHHC6 vs CYP4F29P — PDAC

Explore this scatter interactively →