ZDHHC3

Across TCGA cell cohorts, ZDHHC3 mutation is significantly associated with the RNA expression of many other genes, with 2 significant associations in total. LARGE_INTESTINE shows the largest number of these associations.

The most reproducible ZDHHC3-associated genes across cancer lineages are CFHR2 and CD93. Each is linked with ZDHHC3 in more than 1 cancer types. Because this analysis shows association rather than direction, both ZDHHC3-to-partner and partner-to-ZDHHC3 results are reported.

Each partner links to its own Q-omics profile. The box plot shows the strongest example, CFHR2 grouped by ZDHHC3-low versus ZDHHC3-high in LARGE_INTESTINE.

mutation associated genes by consensus

Ranked by combined sampling and lineage consensus. X-score (ZDHHC3→partner) and Y-score (partner→ZDHHC3) are standardized regression coefficients; both directions are reported because the association is undirected. p-values are from the association test.

Lineage	Partner gene	X-score	Y-score	p(X)	p(Y)	Sampling consensus	Lineage consensus
LARGE_INTESTINE	CFHR2 →	+0.032	+3.700	<.001	.009	3	2
LARGE_INTESTINE	CD93 →	+0.048	+2.994	.003	.006	3	1

Each partner links to its Q-omics profile. Showing the 2 strongest of 2 associations by consensus.

CFHR2 by ZDHHC3 expression — LARGE_INTESTINE

Explore this box plot interactively →