ZDHHC24

Across TCGA cell cohorts, ZDHHC24 RNA expression is significantly associated with the go_rna of many other GO terms, with 4,026 significant associations in total. BLOOD_Leukemia shows the largest number of these associations.

The most reproducible ZDHHC24-associated GO terms across cancer lineages are snoRNA guided rRNA pseudouridine synthesis, Cilium or flagellum-dependent cell motility, and Negative regulation of autophagy. Each is linked with ZDHHC24 in more than 14 cancer types. Because this analysis shows association rather than direction, both ZDHHC24-to-partner and partner-to-ZDHHC24 results are reported.

Each partner links to its own Q-omics profile. The box plot shows the strongest example, snoRNA guided rRNA pseudouridine synthesis grouped by ZDHHC24-low versus ZDHHC24-high in CNS.

RNA expression associated GO terms by consensus

Ranked by combined sampling and lineage consensus. X-score (ZDHHC24→partner) and Y-score (partner→ZDHHC24) are standardized regression coefficients; both directions are reported because the association is undirected. p-values are from the association test.

Lineage	Partner GO term	X-score	Y-score	p(X)	p(Y)	Sampling consensus	Lineage consensus
CNS	snoRNA guided rRNA pseudouridine synthesis →	-0.103	-0.696	<.001	<.001	3	15
OESOPHAGUS	Cilium or flagellum-dependent cell motility →	-0.118	-1.668	<.001	<.001	3	14
OESOPHAGUS	Negative regulation of autophagy →	+0.059	+0.881	.003	<.001	3	14
UPPER_AERODIGESTIVE_TRACT	Flagellated sperm motility →	-0.122	-0.947	.001	<.001	3	14
OESOPHAGUS	Cilium-dependent cell motility →	-0.118	-1.668	<.001	<.001	3	14
UPPER_AERODIGESTIVE_TRACT	Cilium movement involved in cell motility →	-0.123	-1.049	<.001	<.001	3	14

Each partner links to its Q-omics profile. Showing the 6 strongest of 4,026 associations by consensus.

snoRNA guided rRNA pseudouridine synthesis by ZDHHC24 expression — CNS

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