ZDHHC24

Across TCGA cell cohorts, ZDHHC24 mutation is significantly associated with the mutation status of many other genes, with 11 significant associations in total. BLOOD_Leukemia shows the largest number of these associations.

The most reproducible ZDHHC24-associated genes across cancer lineages are TSNAXIP1, TMEM201, and RAD51AP2. Each is linked with ZDHHC24 in more than 1 cancer types. Because this analysis shows association rather than direction, both ZDHHC24-to-partner and partner-to-ZDHHC24 results are reported.

Each partner links to its own Q-omics profile. The box plot shows the strongest example, TSNAXIP1 grouped by ZDHHC24-low versus ZDHHC24-high in BLOOD_Leukemia.

mutation associated genes by consensus

Ranked by combined sampling and lineage consensus. X-score (ZDHHC24→partner) and Y-score (partner→ZDHHC24) are standardized regression coefficients; both directions are reported because the association is undirected. p-values are from the association test.

Lineage	Partner gene	X-score	Y-score	p(X)	p(Y)	Sampling consensus	Lineage consensus
BLOOD_Leukemia	TSNAXIP1 →	+5.321	+5.894	.002	.002	1	2
BLOOD_Leukemia	TMEM201 →	+4.000	+5.050	.008	.008	1	1
BLOOD_Leukemia	RAD51AP2 →	+4.000	+5.050	.008	.008	1	1
BLOOD_Leukemia	DIS3L →	+4.000	+5.050	.008	.008	1	1
BLOOD_Leukemia	APOL3 →	+4.000	+5.050	.008	.008	1	1
BLOOD_Leukemia	GALNT15 →	+4.321	+5.285	.005	.005	1	1

Each partner links to its Q-omics profile. Showing the 6 strongest of 11 associations by consensus.

TSNAXIP1 by ZDHHC24 expression — BLOOD_Leukemia

Explore this box plot interactively →