ZDHHC20P3

Across TCGA pan-cancer cohorts, ZDHHC20P3 RNA is linked to patient survival in 10 of 34 cancer types, making it the most broadly survival-associated ZDHHC20P3 data layer.

The strongest signal is observed in kidney chromophobe (KICH), where higher ZDHHC20P3 RNA is associated with worse disease-free survival. In most high-consensus cancer types, elevated ZDHHC20P3 expression acts as an unfavorable survival marker, although some lineages such as LGG show a favorable association.

KICH, COAD, and ACC are the cancer types where ZDHHC20P3 RNA most reproducibly stratifies survival.

RNA survival associations by lineage

Ranked by sampling consensus. AUC1 and AUC2 indicate survival in the high- and low-expression groups, respectively; the lower AUC marks the poorer-surviving group. p-values are from the log-rank test.

Lineage	Measure	Split	Stage	AUC1 high	AUC2 low	p	Sampling consensus
KICH	DFS	Tertile	All	0.041	0.894	<.001	108	view →
COAD	OS	Tertile	All	0.510	0.879	<.001	108	view →
ACC	DFS	Tertile	III,IV	0.042	0.400	<.001	90	view →
UCS	DFS	Tertile	III,IV	0.146	0.450	.006	72	view →
KIRC	DFS	Tertile	IV	0.226	0.533	.015	26	view →
UCEC	OS	Tertile	All	0.883	0.934	.012	12	view →
LIHC	DFS	Tertile	III,IV	0.094	0.424	.003	12	view →
STAD	DFS	Tertile	IV	0.170	0.487	.020	9	view →
LGG	DFS	Tertile	All	0.901	0.812	.009	6	view →
PCPG	OS	Tertile	All	0.349	1.000	.015	3	view →

Pink = unfavorable, green = favorable. Showing the 10 strongest of 10 lineages.

ZDHHC20P3–KICH (DFS)

Open the KICH breakdown →