ZDHHC20-IT1

Across TCGA pan-cancer cohorts, ZDHHC20-IT1 RNA differs between tumor and matched normal tissue in 11 of 18 cancer types tested, making tumor–normal expression one of ZDHHC20-IT1’s most consistent transcriptional readouts.

The strongest signal is observed in kidney renal clear cell carcinoma (KIRC), where ZDHHC20-IT1 RNA is more highly expressed in tumor relative to normal tissue. In most cancer types ZDHHC20-IT1 is over-expressed in tumor.

KIRC, COAD, and UCEC are the cancer types where ZDHHC20-IT1 tumor–normal differential expression is most reproducible.

RNA tumor vs normal associations by lineage

Ranked by sampling consensus. Fold-change is the tumor-versus-normal difference in ZDHHC20-IT1 RNA (log₂); positive values indicate higher expression in tumor. p-values are from the differential-expression test.

Lineage	Gender	Stage	Fold-change	p	Sampling consensus
KIRC	Female	All	+0.375	<.001	10	view →
COAD	Female	All	+0.927	<.001	9	view →
UCEC	All	All	+0.747	<.001	6	view →
CHOL	All	All	+0.887	<.001	5	view →
BLCA	All	All	+0.332	.022	5	view →
STAD	Male	All	+0.532	.002	4	view →
KIRP	All	III,IV	+0.324	.002	4	view →
LIHC	All	II,III,IV	+0.150	.003	4	view →
BRCA	Female	All	+0.178	.018	3	view →
PRAD	All	All	+0.313	.001	2	view →
READ	All	All	+0.762	.022	1	view →

Pink = over-expressed in tumor, green = repressed in tumor. Showing the 11 strongest of 11 lineages.

ZDHHC20-IT1–KIRC

Open the KIRC breakdown →