ZDHHC19

Across TCGA patient cohorts, ZDHHC19 mutation is significantly associated with the RNA expression of many other genes, with 810 significant associations in total. UCEC shows the largest number of these associations.

The most reproducible ZDHHC19-associated genes across cancer lineages are RNA5SP412, MIR7845, and RNU6-1264P. Each is linked with ZDHHC19 in more than 1 cancer types. Because this analysis shows association rather than direction, both ZDHHC19-to-partner and partner-to-ZDHHC19 results are reported.

Each partner links to its own Q-omics profile. The box plot shows the strongest example, RNA5SP412 grouped by ZDHHC19-low versus ZDHHC19-high in UCEC.

mutation associated genes by consensus

Ranked by combined sampling and lineage consensus. X-score (ZDHHC19→partner) and Y-score (partner→ZDHHC19) are standardized regression coefficients; both directions are reported because the association is undirected. p-values are from the association test.

Lineage	Partner gene	X-score	Y-score	p(X)	p(Y)	Sampling consensus	Lineage consensus
UCEC	RNA5SP412 →	+0.563	+2.230	<.001	.005	3	2
UCEC	MIR7845 →	+0.482	+2.101	<.001	.008	3	2
LUSC	RNU6-1264P →	+0.275	+5.742	<.001	.001	3	2
LUSC	RNU7-130P →	+0.632	+4.993	<.001	.003	3	2
LUAD	LINC01774 →	+0.103	+6.739	.005	<.001	3	2
SKCM	MTCO3P45 →	+0.055	+4.867	<.001	.005	3	2

Each partner links to its Q-omics profile. Showing the 6 strongest of 810 associations by consensus.

RNA5SP412 by ZDHHC19 expression — UCEC

Explore this box plot interactively →