ZDHHC17

mutation — cross-omics
Cross-omicsMUTATION → RNAPatientPairwise association · TCGA cohorts

Across TCGA patient cohorts, ZDHHC17 mutation is significantly associated with the RNA expression of many other genes, with 4,568 significant associations in total. UCEC shows the largest number of these associations.

The most reproducible ZDHHC17-associated genes across cancer lineages are RNA5SP147, LINC02281, and RN7SL163P. Each is linked with ZDHHC17 in more than 1 cancer types. Because this analysis shows association rather than direction, both ZDHHC17-to-partner and partner-to-ZDHHC17 results are reported.

Each partner links to its own Q-omics profile.

mutation associated genes by consensus

Ranked by combined sampling and lineage consensus. X-score (ZDHHC17→partner) and Y-score (partner→ZDHHC17) are standardized regression coefficients; both directions are reported because the association is undirected. p-values are from the association test.
LineagePartner geneX-scoreY-scorep(X)p(Y)Sampling consensusLineage consensus
BRCARNA5SP147 →+0.320+5.324<.001.00332
BRCALINC02281 →+0.160+5.215<.001.00332
BRCARN7SL163P →+0.234+4.736<.001.00332
UCECRCCD1 →+0.523+2.743<.001<.00132
UCECCHAF1A →+0.764+3.565<.001<.00132
UCECPPIP5K1 →+0.371+1.939<.001<.00132
Each partner links to its Q-omics profile. Showing the 6 strongest of 4,568 associations by consensus.

Exploration