ZDHHC16

Across TCGA cell cohorts, ZDHHC16 mutation is significantly associated with the RNA expression of many other genes, with 4 significant associations in total. LARGE_INTESTINE shows the largest number of these associations.

The most reproducible ZDHHC16-associated genes across cancer lineages are OR52B4, NAA11, and MMP26. Each is linked with ZDHHC16 in more than 1 cancer types. Because this analysis shows association rather than direction, both ZDHHC16-to-partner and partner-to-ZDHHC16 results are reported.

Each partner links to its own Q-omics profile. The box plot shows the strongest example, OR52B4 grouped by ZDHHC16-low versus ZDHHC16-high in STOMACH.

mutation associated genes by consensus

Ranked by combined sampling and lineage consensus. X-score (ZDHHC16→partner) and Y-score (partner→ZDHHC16) are standardized regression coefficients; both directions are reported because the association is undirected. p-values are from the association test.

Lineage	Partner gene	X-score	Y-score	p(X)	p(Y)	Sampling consensus	Lineage consensus
STOMACH	OR52B4 →	+0.043	+5.285	<.001	.003	3	1
LARGE_INTESTINE	NAA11 →	+0.344	+3.443	.003	.009	3	1
LARGE_INTESTINE	MMP26 →	+0.033	+3.217	<.001	.006	3	1
LARGE_INTESTINE	TBC1D3 →	+0.051	+3.103	.002	.004	3	1

Each partner links to its Q-omics profile. Showing the 4 strongest of 4 associations by consensus.

OR52B4 by ZDHHC16 expression — STOMACH

Explore this box plot interactively →