ZDHHC15

Across TCGA patient cohorts, ZDHHC15 protein abundance is significantly associated with the RNA expression of many other genes, with 362 significant associations in total. BRCA shows the largest number of these associations.

The most reproducible ZDHHC15-associated genes across cancer lineages are TOP3B, CCDC134, and DEPDC5. Each is linked with ZDHHC15 in more than 1 cancer types. Because this analysis shows association rather than direction, both ZDHHC15-to-partner and partner-to-ZDHHC15 results are reported.

Each partner links to its own Q-omics profile. The scatter plot shows the strongest example, ZDHHC15 versus TOP3B in GBM, with a Pearson correlation of -0.36.

protein abundance associated genes by consensus

Ranked by combined sampling and lineage consensus. X-score (ZDHHC15→partner) and Y-score (partner→ZDHHC15) are standardized regression coefficients; both directions are reported because the association is undirected. p-values are from the association test.

Lineage	Partner gene	X-score	Y-score	p(X)	p(Y)	Sampling consensus	Lineage consensus
GBM	TOP3B →	-0.260	-0.332	.002	<.001	3	1
GBM	CCDC134 →	-0.426	-0.363	<.001	<.001	3	1
GBM	DEPDC5 →	-0.329	-0.279	.001	.002	3	1
GBM	GTPBP1 →	-0.420	-0.316	<.001	<.001	3	1
GBM	LMF2 →	-0.645	-0.446	.001	<.001	3	1
GBM	ASCC2 →	-0.291	-0.305	.002	<.001	3	1

Each partner links to its Q-omics profile. Showing the 6 strongest of 362 associations by consensus.

ZDHHC15 vs TOP3B — GBM

Explore this scatter interactively →