ZDHHC15

Across TCGA cell cohorts, ZDHHC15 RNA expression is significantly associated with the go_rna of many other GO terms, with 1,578 significant associations in total. LUNG_SCLC shows the largest number of these associations.

The most reproducible ZDHHC15-associated GO terms across cancer lineages are Protein targeting to Golgi apparatus, Protein localization to nucleus, and Positive regulation of termination of DNA-templated transcription. Each is linked with ZDHHC15 in more than 6 cancer types. Because this analysis shows association rather than direction, both ZDHHC15-to-partner and partner-to-ZDHHC15 results are reported.

Each partner links to its own Q-omics profile. The box plot shows the strongest example, Protein targeting to Golgi apparatus grouped by ZDHHC15-low versus ZDHHC15-high in SOFT_TISSUE.

RNA expression associated GO terms by consensus

Ranked by combined sampling and lineage consensus. X-score (ZDHHC15→partner) and Y-score (partner→ZDHHC15) are standardized regression coefficients; both directions are reported because the association is undirected. p-values are from the association test.

Lineage	Partner GO term	X-score	Y-score	p(X)	p(Y)	Sampling consensus	Lineage consensus
SOFT_TISSUE	Protein targeting to Golgi apparatus →	-0.220	-1.133	<.001	<.001	3	7
SKIN	Protein localization to nucleus →	+0.046	+0.061	<.001	.004	2	7
OVARY	Positive regulation of termination of DNA-templated transcription →	+0.098	+0.593	.005	.005	3	6
LUNG_SCLC	Transport along microtubule →	+0.067	+1.383	<.001	<.001	3	6
LUNG_SCLC	Regulation of organelle assembly →	+0.052	+1.397	<.001	<.001	3	6
LUNG_SCLC	Regulation of protein modification by small protein conjugation or removal →	+0.044	+1.193	.002	.001	3	6

Each partner links to its Q-omics profile. Showing the 6 strongest of 1,578 associations by consensus.

Protein targeting to Golgi apparatus by ZDHHC15 expression — SOFT_TISSUE

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