ZDHHC14

Across TCGA patient cohorts, ZDHHC14 protein abundance is significantly associated with the RNA expression of many other genes, with 1,184 significant associations in total. GBM shows the largest number of these associations.

The most reproducible ZDHHC14-associated genes across cancer lineages are PLEKHG1, G0S2, and NT5E. Each is linked with ZDHHC14 in more than 1 cancer types. Because this analysis shows association rather than direction, both ZDHHC14-to-partner and partner-to-ZDHHC14 results are reported.

Each partner links to its own Q-omics profile. The scatter plot shows the strongest example, ZDHHC14 versus PLEKHG1 in BRCA, with a Pearson correlation of 0.52.

protein abundance associated genes by consensus

Ranked by combined sampling and lineage consensus. X-score (ZDHHC14→partner) and Y-score (partner→ZDHHC14) are standardized regression coefficients; both directions are reported because the association is undirected. p-values are from the association test.

Lineage	Partner gene	X-score	Y-score	p(X)	p(Y)	Sampling consensus	Lineage consensus
BRCA	PLEKHG1 →	+0.909	+0.750	.008	.009	3	2
BRCA	G0S2 →	+2.983	+0.848	<.001	<.001	3	2
BRCA	NT5E →	+1.570	+0.866	.007	<.001	3	2
BRCA	SERPINE2 →	+1.777	+0.848	<.001	<.001	3	2
GBM	LINC00601 →	+1.029	+0.484	.003	.001	3	2
LSCC	VPS18 →	+0.499	+0.851	.003	<.001	3	1

Each partner links to its Q-omics profile. Showing the 6 strongest of 1,184 associations by consensus.

ZDHHC14 vs PLEKHG1 — BRCA

Explore this scatter interactively →