Across TCGA patient cohorts, ZDHHC11 mutation is significantly associated with the RNA expression of many other genes, with 2,529 significant associations in total. UCEC shows the largest number of these associations.

The most reproducible ZDHHC11-associated genes across cancer lineages are GAMTP2, RN7SL248P, and ZFAND2A. Each is linked with ZDHHC11 in more than 1 cancer types. Because this analysis shows association rather than direction, both ZDHHC11-to-partner and partner-to-ZDHHC11 results are reported.

Each partner links to its own Q-omics profile.

mutation associated genes by consensus

Ranked by combined sampling and lineage consensus. X-score (ZDHHC11→partner) and Y-score (partner→ZDHHC11) are standardized regression coefficients; both directions are reported because the association is undirected. p-values are from the association test.

Lineage	Partner gene	X-score	Y-score	p(X)	p(Y)	Sampling consensus	Lineage consensus
CESC	GAMTP2 →	+0.085	+5.342	<.001	.002	3	2
UCEC	RN7SL248P →	+0.062	+3.219	<.001	.004	3	2
UCEC	ZFAND2A →	+0.543	+3.480	<.001	.002	3	2
UCEC	FAM118A →	+0.405	+4.258	.009	<.001	3	2
UCEC	PARD6A →	+0.769	+3.343	<.001	.005	3	2
SKCM	SNORD116-13 →	+0.517	+2.386	.001	.008	3	2

Each partner links to its Q-omics profile. Showing the 6 strongest of 2,529 associations by consensus.

Exploration

ZDHHC11 survival (RNA) · tumor vs normal (RNA) · all ZDHHC11 data types