ZCCHC9

Across TCGA patient cohorts, ZCCHC9 RNA expression is significantly associated with the protein abundance of many other proteins, with 13,113 significant associations in total. GBM shows the largest number of these associations.

The most reproducible ZCCHC9-associated proteins across cancer lineages are MSH3, SDF2L1, and CERT1. Each is linked with ZCCHC9 in more than 7 cancer types. Because this analysis shows association rather than direction, both ZCCHC9-to-partner and partner-to-ZCCHC9 results are reported.

Each partner links to its own Q-omics profile. The scatter plot shows the strongest example, ZCCHC9 versus MSH3 in LSCC, with a Pearson correlation of 0.45.

RNA expression associated proteins by consensus

Ranked by combined sampling and lineage consensus. X-score (ZCCHC9→partner) and Y-score (partner→ZCCHC9) are standardized regression coefficients; both directions are reported because the association is undirected. p-values are from the association test.

Lineage	Partner protein	X-score	Y-score	p(X)	p(Y)	Sampling consensus	Lineage consensus
LSCC	MSH3 →	+0.413	+0.447	<.001	<.001	3	8
BRCA	SDF2L1 →	-0.461	-0.471	<.001	<.001	3	5
PDAC	CERT1 →	+0.220	+0.341	<.001	<.001	3	5
OV	CHD1 →	+0.375	+0.482	.001	<.001	3	5
HNSC	CRELD2 →	-0.622	-0.498	<.001	<.001	3	5
OV	ATXN2L →	+0.327	+0.330	.002	.006	3	5

Each partner links to its Q-omics profile. Showing the 6 strongest of 13,113 associations by consensus.

ZCCHC9 vs MSH3 — LSCC

Explore this scatter interactively →