ZCCHC24

Across TCGA patient cohorts, ZCCHC24 protein abundance is significantly associated with the RNA expression of many other genes, with 18,030 significant associations in total. LSCC shows the largest number of these associations.

The most reproducible ZCCHC24-associated genes across cancer lineages are PODN, SRPX, and ECM2. Each is linked with ZCCHC24 in more than 9 cancer types. Because this analysis shows association rather than direction, both ZCCHC24-to-partner and partner-to-ZCCHC24 results are reported.

Each partner links to its own Q-omics profile. The scatter plot shows the strongest example, ZCCHC24 versus PODN in BRCA, with a Pearson correlation of 0.80.

protein abundance associated genes by consensus

Ranked by combined sampling and lineage consensus. X-score (ZCCHC24→partner) and Y-score (partner→ZCCHC24) are standardized regression coefficients; both directions are reported because the association is undirected. p-values are from the association test.

Lineage	Partner gene	X-score	Y-score	p(X)	p(Y)	Sampling consensus	Lineage consensus
BRCA	PODN →	+2.085	+0.763	<.001	<.001	3	10
OV	SRPX →	+1.563	+0.802	<.001	<.001	3	9
BRCA	ECM2 →	+1.727	+0.747	<.001	<.001	3	9
CCRCC	DCN →	+2.158	+0.379	<.001	<.001	3	9
BRCA	TGFB3 →	+1.531	+0.654	<.001	<.001	3	9
BRCA	CNRIP1 →	+1.123	+0.725	<.001	<.001	3	9

Each partner links to its Q-omics profile. Showing the 6 strongest of 18,030 associations by consensus.

ZCCHC24 vs PODN — BRCA

Explore this scatter interactively →