ZCCHC17

Across TCGA patient cohorts, ZCCHC17 protein abundance is significantly associated with the RNA expression of many other genes, with 14,664 significant associations in total. GBM shows the largest number of these associations.

The most reproducible ZCCHC17-associated genes across cancer lineages are CDCA8, ITGB3BP, and CCDC150. Each is linked with ZCCHC17 in more than 5 cancer types. Because this analysis shows association rather than direction, both ZCCHC17-to-partner and partner-to-ZCCHC17 results are reported.

Each partner links to its own Q-omics profile. The scatter plot shows the strongest example, ZCCHC17 versus CDCA8 in BRCA, with a Pearson correlation of 0.40.

protein abundance associated genes by consensus

Ranked by combined sampling and lineage consensus. X-score (ZCCHC17→partner) and Y-score (partner→ZCCHC17) are standardized regression coefficients; both directions are reported because the association is undirected. p-values are from the association test.

Lineage	Partner gene	X-score	Y-score	p(X)	p(Y)	Sampling consensus	Lineage consensus
BRCA	CDCA8 →	+1.313	+0.369	<.001	<.001	3	6
GBM	ITGB3BP →	+0.544	+0.256	<.001	.004	3	6
UCEC	CCDC150 →	+0.911	+0.208	<.001	<.001	3	6
LSCC	CEP85 →	+0.548	+0.267	<.001	<.001	3	5
LSCC	RCC1 →	+0.748	+0.406	<.001	<.001	3	5
LSCC	SNRNP40 →	+0.464	+0.292	<.001	<.001	3	5

Each partner links to its Q-omics profile. Showing the 6 strongest of 14,664 associations by consensus.

ZCCHC17 vs CDCA8 — BRCA

Explore this scatter interactively →