ZCCHC13

mutation — cross-omics
Cross-omicsMUTATION → RNAPatientPairwise association · TCGA cohorts

Across TCGA patient cohorts, ZCCHC13 mutation is significantly associated with the RNA expression of many other genes, with 2,642 significant associations in total. UCEC shows the largest number of these associations.

The most reproducible ZCCHC13-associated genes across cancer lineages are CYCSP26, GEMIN4, and EXOC5P1. Each is linked with ZCCHC13 in more than 1 cancer types. Because this analysis shows association rather than direction, both ZCCHC13-to-partner and partner-to-ZCCHC13 results are reported.

Each partner links to its own Q-omics profile.

mutation associated genes by consensus

Ranked by combined sampling and lineage consensus. X-score (ZCCHC13→partner) and Y-score (partner→ZCCHC13) are standardized regression coefficients; both directions are reported because the association is undirected. p-values are from the association test.
LineagePartner geneX-scoreY-scorep(X)p(Y)Sampling consensusLineage consensus
UCECCYCSP26 →+0.100+2.599.004.00632
UCECGEMIN4 →+0.585+3.379.001.00432
UCECEXOC5P1 →+0.209+2.653<.001<.00132
UCECNF2 →+0.600+2.233<.001.00632
UCECRN7SKP230 →+0.334+1.994<.001.00732
COADRNU6-42P →+0.955+3.105<.001.00432
Each partner links to its Q-omics profile. Showing the 6 strongest of 2,642 associations by consensus.

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