ZCCHC12

Across TCGA cell cohorts, ZCCHC12 protein abundance is significantly associated with the RNA expression of many other genes, with 2,467 significant associations in total. SKIN shows the largest number of these associations.

The most reproducible ZCCHC12-associated genes across cancer lineages are SDCBP, NSMAF, and FOSL1. Each is linked with ZCCHC12 in more than 15 cancer types. Because this analysis shows association rather than direction, both ZCCHC12-to-partner and partner-to-ZCCHC12 results are reported.

Each partner links to its own Q-omics profile. The scatter plot shows the strongest example, ZCCHC12 versus SDCBP in URINARY_TRACT, with a Pearson correlation of 0.65.

protein abundance associated genes by consensus

Ranked by combined sampling and lineage consensus. X-score (ZCCHC12→partner) and Y-score (partner→ZCCHC12) are standardized regression coefficients; both directions are reported because the association is undirected. p-values are from the association test.

Lineage	Partner gene	X-score	Y-score	p(X)	p(Y)	Sampling consensus	Lineage consensus
URINARY_TRACT	SDCBP →	+1.787	+2.182	.005	<.001	2	16
BREAST	NSMAF →	+1.512	+1.844	.008	.004	3	7
OVARY	FOSL1 →	+3.157	+1.352	.001	.001	2	7
LIVER	PLEC →	+1.633	+2.164	.006	<.001	3	5
BREAST	CORO1C →	+1.152	+1.671	.007	.009	3	5
LUNG_NSCLC_LUSC	PHC2 →	+1.571	+1.495	.002	.003	3	5

Each partner links to its Q-omics profile. Showing the 6 strongest of 2,467 associations by consensus.

ZCCHC12 vs SDCBP — URINARY_TRACT

Explore this scatter interactively →