ZCCHC10

Across TCGA patient cohorts, ZCCHC10 protein abundance is significantly associated with the RNA expression of many other genes, with 1,577 significant associations in total. GBM shows the largest number of these associations.

The most reproducible ZCCHC10-associated genes across cancer lineages are ATXN7L2, ASXL1, and CCNL2. Each is linked with ZCCHC10 in more than 1 cancer types. Because this analysis shows association rather than direction, both ZCCHC10-to-partner and partner-to-ZCCHC10 results are reported.

Each partner links to its own Q-omics profile. The scatter plot shows the strongest example, ZCCHC10 versus ATXN7L2 in GBM, with a Pearson correlation of 0.42.

protein abundance associated genes by consensus

Ranked by combined sampling and lineage consensus. X-score (ZCCHC10→partner) and Y-score (partner→ZCCHC10) are standardized regression coefficients; both directions are reported because the association is undirected. p-values are from the association test.

Lineage	Partner gene	X-score	Y-score	p(X)	p(Y)	Sampling consensus	Lineage consensus
GBM	ATXN7L2 →	+0.523	+0.439	<.001	<.001	3	2
GBM	ASXL1 →	+0.367	+0.286	<.001	.006	3	2
UCEC	CCNL2 →	+0.523	+0.447	.002	.004	3	2
UCEC	SNHG20 →	+0.428	+0.393	.003	.004	3	2
UCEC	MAP3K14-AS1 →	+0.614	+0.451	<.001	.003	3	2
UCEC	CIRBP-AS1 →	+0.361	+0.317	.009	.002	3	2

Each partner links to its Q-omics profile. Showing the 6 strongest of 1,577 associations by consensus.

ZCCHC10 vs ATXN7L2 — GBM

Explore this scatter interactively →