ZC4H2

Across TCGA patient cohorts, ZC4H2 RNA expression is significantly associated with the protein abundance of many other proteins, with 16,330 significant associations in total. LSCC shows the largest number of these associations.

The most reproducible ZC4H2-associated proteins across cancer lineages are DDAH2, FAM83H, and TNS3_S969. Each is linked with ZC4H2 in more than 4 cancer types. Because this analysis shows association rather than direction, both ZC4H2-to-partner and partner-to-ZC4H2 results are reported.

Each partner links to its own Q-omics profile. The scatter plot shows the strongest example, ZC4H2 versus DDAH2 in GBM, with a Pearson correlation of 0.31.

RNA expression associated proteins by consensus

Ranked by combined sampling and lineage consensus. X-score (ZC4H2→partner) and Y-score (partner→ZC4H2) are standardized regression coefficients; both directions are reported because the association is undirected. p-values are from the association test.

Lineage	Partner protein	X-score	Y-score	p(X)	p(Y)	Sampling consensus	Lineage consensus
GBM	DDAH2 →	+0.369	+0.626	.001	.005	3	5
GBM	FAM83H →	-0.735	-1.031	<.001	<.001	3	5
LSCC	TNS3_S969 →	+0.571	+0.551	<.001	<.001	3	4
CCRCC	NDUFAB1 →	-0.336	-0.395	<.001	.007	3	4
PDAC	SEPTIN7 →	+0.362	+0.462	<.001	<.001	3	4
HNSC	GLTP →	-0.437	-0.547	.008	<.001	3	4

Each partner links to its Q-omics profile. Showing the 6 strongest of 16,330 associations by consensus.

ZC4H2 vs DDAH2 — GBM

Explore this scatter interactively →