ZC4H2

mutation — cross-omics
Cross-omicsMUTATION → RNACell-linePairwise association · TCGA cohorts

Across TCGA cell cohorts, ZC4H2 mutation is significantly associated with the RNA expression of many other genes, with 1 significant associations in total. SKIN shows the largest number of these associations.

The most reproducible ZC4H2-associated genes across cancer lineages are TBC1D3H. Each is linked with ZC4H2 in more than 1 cancer types. Because this analysis shows association rather than direction, both ZC4H2-to-partner and partner-to-ZC4H2 results are reported.

Each partner links to its own Q-omics profile. The box plot shows the strongest example, TBC1D3H grouped by ZC4H2-low versus ZC4H2-high in SKIN.

mutation associated genes by consensus

Ranked by combined sampling and lineage consensus. X-score (ZC4H2→partner) and Y-score (partner→ZC4H2) are standardized regression coefficients; both directions are reported because the association is undirected. p-values are from the association test.
LineagePartner geneX-scoreY-scorep(X)p(Y)Sampling consensusLineage consensus
SKINTBC1D3H →+0.648+4.095<.001.00931
Each partner links to its Q-omics profile. Showing the 1 strongest of 1 associations by consensus.

TBC1D3H by ZC4H2 expression — SKIN

Box plot of TBC1D3H in ZC4H2-low vs ZC4H2-high samples in SKIN.

Explore this box plot interactively →

Exploration