ZC3H8

Across TCGA pan-cancer cohorts, ZC3H8 Mutation is linked to patient survival in 1 of 34 cancer types, making it a survival-associated ZC3H8 data layer compared with 22 for mass-spec protein and 5 for mass-spec protein.

The strongest signal is observed in bladder urothelial carcinoma (BLCA), where higher ZC3H8 Mutation is associated with worse disease-free survival. In most high-consensus cancer types, elevated ZC3H8 expression acts as an unfavorable survival marker.

BLCA are the cancer types where ZC3H8 Mutation most reproducibly stratifies survival.

Mutation survival associations by lineage

Ranked by sampling consensus. AUC1 and AUC2 indicate survival in the high- and low-expression groups, respectively; the lower AUC marks the poorer-surviving group. p-values are from the log-rank test.

Lineage	Measure	Split	Stage	AUC1 high	AUC2 low	p	Sampling consensus
BLCA	DFS	Median	All	0.015	0.616	<.001	12	view →

Pink = unfavorable, green = favorable. Showing the 1 strongest of 1 lineages.

ZC3H8–BLCA (DFS)

Open the BLCA breakdown →