ZC3H7B

Across TCGA patient cohorts, ZC3H7B protein abundance is significantly associated with the RNA expression of many other genes, with 5,510 significant associations in total. GBM shows the largest number of these associations.

The most reproducible ZC3H7B-associated genes across cancer lineages are DESI1, XRCC6, and TOMM22. Each is linked with ZC3H7B in more than 7 cancer types. Because this analysis shows association rather than direction, both ZC3H7B-to-partner and partner-to-ZC3H7B results are reported.

Each partner links to its own Q-omics profile. The scatter plot shows the strongest example, ZC3H7B versus DESI1 in OV, with a Pearson correlation of 0.47.

protein abundance associated genes by consensus

Ranked by combined sampling and lineage consensus. X-score (ZC3H7B→partner) and Y-score (partner→ZC3H7B) are standardized regression coefficients; both directions are reported because the association is undirected. p-values are from the association test.

Lineage	Partner gene	X-score	Y-score	p(X)	p(Y)	Sampling consensus	Lineage consensus
OV	DESI1 →	+0.561	+0.296	<.001	<.001	3	8
BRCA	XRCC6 →	+0.548	+0.237	<.001	<.001	3	6
BRCA	TOMM22 →	+0.567	+0.251	<.001	<.001	3	6
LSCC	ATXN10 →	+0.533	+0.145	<.001	<.001	3	6
HNSC	XPNPEP3 →	+0.447	+0.119	.001	.003	3	6
OV	ANKRD54 →	+0.525	+0.226	<.001	.001	3	5

Each partner links to its Q-omics profile. Showing the 6 strongest of 5,510 associations by consensus.

ZC3H7B vs DESI1 — OV

Explore this scatter interactively →