ZC3H7B

Across TCGA cell cohorts, ZC3H7B RNA expression is significantly associated with the go_rna of many other GO terms, with 4,502 significant associations in total. BLOOD_Leukemia shows the largest number of these associations.

The most reproducible ZC3H7B-associated GO terms across cancer lineages are Negative regulation of chromosome condensation, Regulation of Golgi inheritance, and CAMP/PKA signal transduction. Each is linked with ZC3H7B in more than 16 cancer types. Because this analysis shows association rather than direction, both ZC3H7B-to-partner and partner-to-ZC3H7B results are reported.

Each partner links to its own Q-omics profile. The box plot shows the strongest example, Negative regulation of chromosome condensation grouped by ZC3H7B-low versus ZC3H7B-high in UPPER_AERODIGESTIVE_TRACT.

RNA expression associated GO terms by consensus

Ranked by combined sampling and lineage consensus. X-score (ZC3H7B→partner) and Y-score (partner→ZC3H7B) are standardized regression coefficients; both directions are reported because the association is undirected. p-values are from the association test.

Lineage	Partner GO term	X-score	Y-score	p(X)	p(Y)	Sampling consensus	Lineage consensus
UPPER_AERODIGESTIVE_TRACT	Negative regulation of chromosome condensation →	+0.192	+1.346	<.001	<.001	3	17
UPPER_AERODIGESTIVE_TRACT	Regulation of Golgi inheritance →	+0.194	+1.419	<.001	<.001	3	15
URINARY_TRACT	CAMP/PKA signal transduction →	+0.188	+1.043	<.001	<.001	3	14
STOMACH	Symbiont-mediated disruption of host cellular anatomical structure →	+0.133	+0.759	<.001	.002	2	15
STOMACH	Symbiont-mediated disruption of host anatomical structure →	+0.133	+0.759	<.001	.002	2	15
KIDNEY	Interleukin-34-mediated signaling pathway →	+0.249	+0.884	.002	.002	3	14

Each partner links to its Q-omics profile. Showing the 6 strongest of 4,502 associations by consensus.

Negative regulation of chromosome condensation by ZC3H7B expression — UPPER_AERODIGESTIVE_TRACT

Explore this box plot interactively →