ZC3H7A

Across TCGA patient cohorts, ZC3H7A RNA expression is significantly associated with the protein abundance of many other proteins, with 13,494 significant associations in total. BRCA shows the largest number of these associations.

The most reproducible ZC3H7A-associated proteins across cancer lineages are PDS5B, CHAMP1, and HCFC1. Each is linked with ZC3H7A in more than 5 cancer types. Because this analysis shows association rather than direction, both ZC3H7A-to-partner and partner-to-ZC3H7A results are reported.

Each partner links to its own Q-omics profile. The scatter plot shows the strongest example, ZC3H7A versus PDS5B in GBM, with a Pearson correlation of 0.48.

RNA expression associated proteins by consensus

Ranked by combined sampling and lineage consensus. X-score (ZC3H7A→partner) and Y-score (partner→ZC3H7A) are standardized regression coefficients; both directions are reported because the association is undirected. p-values are from the association test.

Lineage	Partner protein	X-score	Y-score	p(X)	p(Y)	Sampling consensus	Lineage consensus
GBM	PDS5B →	+0.373	+0.383	<.001	<.001	3	5
GBM	CHAMP1 →	+0.461	+0.469	<.001	<.001	3	5
GBM	HCFC1 →	+0.299	+0.388	<.001	<.001	3	5
CCRCC	MAZ →	+0.496	+0.301	<.001	<.001	2	6
OV	SLC25A5 →	-0.504	-0.455	<.001	.001	3	4
HNSC	PARP1 →	+0.530	+0.368	<.001	.001	3	4

Each partner links to its Q-omics profile. Showing the 6 strongest of 13,494 associations by consensus.

ZC3H7A vs PDS5B — GBM

Explore this scatter interactively →