ZC3H7A

Across TCGA patient cohorts, ZC3H7A protein abundance is significantly associated with the RNA expression of many other genes, with 8,873 significant associations in total. LSCC shows the largest number of these associations.

The most reproducible ZC3H7A-associated genes across cancer lineages are SEC11C, TXNDC11, and NDRG1. Each is linked with ZC3H7A in more than 4 cancer types. Because this analysis shows association rather than direction, both ZC3H7A-to-partner and partner-to-ZC3H7A results are reported.

Each partner links to its own Q-omics profile. The scatter plot shows the strongest example, ZC3H7A versus SEC11C in LUAD, with a Pearson correlation of 0.35.

protein abundance associated genes by consensus

Ranked by combined sampling and lineage consensus. X-score (ZC3H7A→partner) and Y-score (partner→ZC3H7A) are standardized regression coefficients; both directions are reported because the association is undirected. p-values are from the association test.

Lineage	Partner gene	X-score	Y-score	p(X)	p(Y)	Sampling consensus	Lineage consensus
LUAD	SEC11C →	+0.692	+0.114	<.001	.003	3	5
UCEC	TXNDC11 →	+0.468	+0.162	<.001	<.001	3	4
LSCC	NDRG1 →	-1.459	-0.144	<.001	.001	3	3
BRCA	CHRAC1 →	-0.621	-0.169	<.001	.001	3	3
COAD	DDX59 →	+0.319	+0.178	.003	<.001	3	3
COAD	CASP8AP2 →	+0.341	+0.224	.009	<.001	3	3

Each partner links to its Q-omics profile. Showing the 6 strongest of 8,873 associations by consensus.

ZC3H7A vs SEC11C — LUAD

Explore this scatter interactively →