ZC3H7A

Across TCGA patient cohorts, ZC3H7A protein abundance is significantly associated with the protein abundance of many other proteins, with 16,561 significant associations in total. CCRCC shows the largest number of these associations.

The most reproducible ZC3H7A-associated proteins across cancer lineages are ZNF330, GSPT1, and SLC2A1. Each is linked with ZC3H7A in more than 5 cancer types. Because this analysis shows association rather than direction, both ZC3H7A-to-partner and partner-to-ZC3H7A results are reported.

Each partner links to its own Q-omics profile. The scatter plot shows the strongest example, ZC3H7A versus ZNF330 in CCRCC, with a Pearson correlation of 0.55.

protein abundance associated proteins by consensus

Ranked by combined sampling and lineage consensus. X-score (ZC3H7A→partner) and Y-score (partner→ZC3H7A) are standardized regression coefficients; both directions are reported because the association is undirected. p-values are from the association test.

Lineage	Partner protein	X-score	Y-score	p(X)	p(Y)	Sampling consensus	Lineage consensus
CCRCC	ZNF330 →	+0.419	+0.155	<.001	<.001	3	6
UCEC	GSPT1 →	+0.338	+0.203	<.001	<.001	3	6
LSCC	SLC2A1 →	-1.045	-0.190	<.001	<.001	3	6
CCRCC	SPTB →	-1.113	-0.166	<.001	<.001	3	6
CCRCC	APOM →	-0.618	-0.133	<.001	<.001	3	5
BRCA	ARCN1 →	+0.223	+0.185	.001	<.001	3	5

Each partner links to its Q-omics profile. Showing the 6 strongest of 16,561 associations by consensus.

ZC3H7A vs ZNF330 — CCRCC

Explore this scatter interactively →