ZC3H18

Across TCGA cell cohorts, ZC3H18 mutation is significantly associated with the RNA expression of many other genes, with 676 significant associations in total. LARGE_INTESTINE shows the largest number of these associations.

The most reproducible ZC3H18-associated genes across cancer lineages are OOSP3, AHSA1, and RAP1GDS1. Each is linked with ZC3H18 in more than 2 cancer types. Because this analysis shows association rather than direction, both ZC3H18-to-partner and partner-to-ZC3H18 results are reported.

Each partner links to its own Q-omics profile. The box plot shows the strongest example, OOSP3 grouped by ZC3H18-low versus ZC3H18-high in BLOOD_Lymphoma.

mutation associated genes by consensus

Ranked by combined sampling and lineage consensus. X-score (ZC3H18→partner) and Y-score (partner→ZC3H18) are standardized regression coefficients; both directions are reported because the association is undirected. p-values are from the association test.

Lineage	Partner gene	X-score	Y-score	p(X)	p(Y)	Sampling consensus	Lineage consensus
BLOOD_Lymphoma	OOSP3 →	+0.112	+3.579	<.001	.007	3	3
LARGE_INTESTINE	AHSA1 →	+0.527	+3.588	<.001	<.001	3	2
LARGE_INTESTINE	RAP1GDS1 →	+0.606	+3.502	.001	.001	3	2
LARGE_INTESTINE	OXNAD1 →	+0.511	+3.502	<.001	.001	3	2
LARGE_INTESTINE	ZFAND4 →	+1.000	+3.502	<.001	.001	3	2
LARGE_INTESTINE	FOXE3 →	+0.097	+3.237	.001	.003	3	2

Each partner links to its Q-omics profile. Showing the 6 strongest of 676 associations by consensus.

OOSP3 by ZC3H18 expression — BLOOD_Lymphoma

Explore this box plot interactively →